It seemed like the perfect time for Sean Payton to try an onside kick under he NFL's new kickoff rules that only allow them ...

The Niners ruled out the Pro Bowl running back Friday, with Niners head coach Kyle Shanahan telling reporters the team is ...

Niners cornerback Deommodore Lenoir is ready to face the QB he saw plenty in practice last season, adding he and Vikings' Sam ...

Last season's AP Offensive Player of the Year missed the season opener, and now will have to sit out at least four more games ...

Justin Jefferson is mad-good. The great wide received scorched the San Francisco 49ers on Sunday to the tune of a 97-yard ...

The Minnesota Vikings defense stops the San Francisco 49ers on a 4th-and goal thanks to a tipped pass from Vikings linebacker ...

Minnesota Vikings Head Coach Kevin O'Connell joins Colin Cowherd to discuss how Sam Darnold's San Francisco 49ers tenure has ...

NFL futures: AFC favorites include the Kansas City Chiefs (+240), Texans, Bills, and Ravens. In the NFC, leaders are the San ...

Prove it. Join our new, free-to-play Niners Wire Challenge. Answer eight questions below, plus a tie breaker correctly for ...

No Christian McCaffrey. No problem. The San Francisco 49ers got into the win column right out of the gate in Week 1, ...