Just as the San Francisco 49ers won’t miss seeing Aaron Donald lining up for the Los Angeles Rams on Sunday, Sean McVay won’t ...

The 49ers are partly to blame for why Christian McCaffrey will be out at least four games and possibly more as he nurses ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

Alvin Kamara surpassed Christian McCaffrey in career touchdowns scored, ranking sixth-best among active players. Klint Kubiak ...

Kyle Shanahan often couches any comments about the health of his players by noting the obvious: He’s not a doctor. However, ...

The San Francisco 49ers have placed All-Pro running back Christian McCaffrey on injured reserve because of his lingering calf ...

The San Francisco 49ers announced that star running back Christian McCaffrey, who missed the season opener because of ...

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

With injuries sidelining their star athletes, can the 49ers rally together to secure a crucial win against the desperate Rams ...

San Francisco 49ers running back Christian McCaffrey has been placed on the injured reserve, but could miss more time after, ...

Who's going to be the first to blame Christian McCaffrey's injury on the Madden curse?