The 49ers looked incredible on Monday, and now they face a road test against a Vikings team that was good ... against the ...

Last season's AP Offensive Player of the Year missed the season opener, and now will have to sit out at least four more games ...

The lingering calf and Achilles tendon injuries means the All-Pro running back won't be eligible to return until a Thursday ...

Niners cornerback Deommodore Lenoir is ready to face the QB he saw plenty in practice last season, adding he and Vikings' Sam ...

The San Francisco 49ers have ruled running back Christian McCaffrey out for their Week 2 game at the Minnesota Vikings, and a ...

The 49ers will decide this weekend whether or not to place number 23 on the injured reserve list for four weeks or to keep ...

The Niners ruled out the Pro Bowl running back Friday, with Niners head coach Kyle Shanahan telling reporters the team is ...

All-Pro running back Christian McCaffrey has been ruled out of this weekend’s game for the San Francisco 49ers because of his ...

Minnesota Vikings Head Coach Kevin O'Connell joins Colin Cowherd to discuss how Sam Darnold's San Francisco 49ers tenure has ...

Questions this week include why the 49ers were reluctant to play Jacob Cowing and whether they're working on any contract ...

Christian McCaffrey was ruled out of the Minnesota game Friday and could be headed for injured reserve. McCaffrey was not on ...

Coach Kyle Shanahan insisted star Christian McCaffrey was a game-time decision. Backup Jordan Mason may have known he'd get ...