Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses. These proteins play ...

First, they must enter the host cells, which RSV does using its fusion (F) protein. Vaccines induce antibodies that bind to pathogens. Neutralizing antibodies bind to crucial sites, such as part ...

Scanning electron micrograph of human respiratory syncytial virus (RSV) virions (colorized blue) and tagged with antibodies (colorized yellow) against the virus’ fusion protein — the target of ...

McLellan, who will be inducted in Washington, D.C. on May 8, is among the youngest new inductees in hall of fame history.

The trimeric pre-fusion glycoprotein F is essential for accurately assessing the immunogenicity of RSV vaccines. We strictly adhere to ... whether it comes through recombinant proteins, antibodies, ...

which used McLellan and Graham’s research to stabilize the RSV fusion protein and enable the body to develop strong antibodies against it, according to UT. “Getting into structure-based vacc ...

Testing was performed using BinaxNOW RSV immunochromatographic assays to detect RSV fusion protein antigen in nasopharyngeal swabs (93% sensitivity, 93% specificity, Alere Scarborough Inc ...

The adjuvanted RSV prefusion F protein-based vaccine RSVPreF3-AS01E ... tended to have higher levels of RSV-neutralizing, anti-pre-fusion F antibodies," according to a statement by Werbel.

The two vaccines induce the immune system to target a critical protein on the surface of RSV, the F protein, in its pre-infection form, known as pre-fusion F. High levels of antibodies against pre ...