The 49ers are in a tough spot. They didn't play this weekend, but every other team in their division did. And the Cardinals ...

Shannon Sharpe has the utmost confidence in the 49ers to make a late-season run and ... I expect them to come out and win the NFC West and make a strong run into the playoffs.” ...

That was one surefire way for the injury-stung 49ers to snap out of an October funk ... tribute day that he helped create. “To get a win is very helpful.” Someone else needed to come off ...

It has been a rough month for Biff Poggi and the Charlotte 49ers, but even in an up-and-down season with just three opportunities games left, Charlotte still controls its own bowl-eligibility destiny.

LA is technically ahead of the 49ers because they hold the head-to-head tiebreaker. With the win by the Cardinals, the 49ers ...

San Francisco 49ers running back Christian McCaffrey made his return to practice on Monday, with Nick Wagoner of ESPN posting video of the star in action. NFL Network's Tom Pelissero reported San ...

The San Francisco 49ers officially opened McCaffrey's practice window on Monday. McCaffrey has been sidelined since training camp with calf and Achilles ailments and now has 21 days for the 49ers ...

This isn't the first time Harbaugh has matched his predecessor's final win total early in the season, though. His first season with the 49ers resulted in a 13-3 record after San Francisco went 6 ...

The San Francisco 49ers announced they have waived LB Jalen Graham from the team's active roster and released K Anders Carlson from the practice squad. Graham (6-3, 220) originally signed to the ...

The off week came at the perfect time for the banged-up 49ers, who are still the favorites in the NFC West. The Rams have won three straight and they got their first win on the road Sunday.