Charlie Sheen's brief and impactful cameo in The Big Bang Theory quickly eclipsed the show's main stars in just a few moments ...

Mayim Bialik, who plays neuroscientist Amy Farrah Fowler, opened up about The Big Bang Theory's main star, Jim Parsons, and explained what many fans already know: why he's so good at playing Sheldon ...

Instead, the entertainment industry was buzzing about the fact that the main cast of "The Big Bang Theory" — Jim Parsons, Johnny Galecki, Simon Helberg, Kunal Nayyar, Kaley Cuoco, Melissa Rauch ...

American sitcom The Big Bang Theory centers around friends Leonard Hofstadter (Johnny Galecki), Sheldon Cooper (Jim Parsons), Penny ... and Raj Koothrappali (Kunal Nayyar). Supporting characters ...