But some 80 percent of people with Parkinson's disease have GI problems, such as acid reflux, irritable bowel syndrome, and constipation, which often emerge decades before motor difficulties do. This ...

Andreasson and colleagues have found, using both in vitro and in vivo models, that kynurenine (Kyn) generated by IDO1 ...

On Tuesday September 10, Francisco Lopera died of cancer at his home in Medellin, Colombia. He was 73, and only just beginning to see his life’s work come to fruition.

Lo and behold, he found a 317-bp AluYb8 retrotransposon lurking within the 3ˈUTR of people who carried the SNPs corresponding ...

A study published June 26 in Science Translational Medicine adds to the growing pile of proteomics data implicating cellular processes such as autophagy, ubiquitination, endocytosis, and glycolysis as ...

Could one tiny little amino acid derivative make Alzheimer’s disease a whole lot worse? In the August 25 Science, researchers led by Katrin Andreasson, Stanford University School of Medicine, report ...

In Alzheimer’s disease, tau tangles accumulate in the temporal lobe and cortex, but spare other regions such as the cerebellum and brainstem. In a July 31 preprint on bioRxiv, scientists led by Huda ...

Decades before memory loss becomes a concern, the biological processes that lead to Alzheimer’s disease are underway in the brain. Could proteins in the blood sound the alarm for this pending crisis?

I am a co-founder of Treventis Corp. which is a startup biotech dedicated to the design and development of novel small molecule inhibitors of beta-amyloid and tau misfolding and oligomerization.