But some 80 percent of people with Parkinson's disease have GI problems, such as acid reflux, irritable bowel syndrome, and constipation, which often emerge decades before motor difficulties do. This ...

On Tuesday September 10, Francisco Lopera died of cancer at his home in Medellin, Colombia. He was 73, and only just beginning to see his life’s work come to fruition.

Lo and behold, he found a 317-bp AluYb8 retrotransposon lurking within the 3ˈUTR of people who carried the SNPs corresponding ...

In Alzheimer’s disease, tau tangles accumulate in the temporal lobe and cortex, but spare other regions such as the cerebellum and brainstem. In a July 31 preprint on bioRxiv, scientists led by Huda ...

Andreasson and colleagues have found, using both in vitro and in vivo models, that kynurenine (Kyn) generated by IDO1 ...

A study published June 26 in Science Translational Medicine adds to the growing pile of proteomics data implicating cellular processes such as autophagy, ubiquitination, endocytosis, and glycolysis as ...

I am a co-founder of Treventis Corp. which is a startup biotech dedicated to the design and development of novel small molecule inhibitors of beta-amyloid and tau misfolding and oligomerization.

A group of 17 plasma proteins were tied to AD only in ApoE4 carriers, and their expression appeared regulated by ApoE4. Curiously, four of these were downregulated by ApoE4, yet upregulated as AD ...

Could one tiny little amino acid derivative make Alzheimer’s disease a whole lot worse? In the August 25 Science, researchers led by Katrin Andreasson, Stanford University School of Medicine, report ...