The San Francisco 49ers are making their first moves after confirming that Brandon Aiyuk tore his ACL and MCL this past ...

The San Francisco 49ers are dealing with a rash of injuries, mainly to top offensive players, and none may be worse than ...

Brandon Aiyuk has been placed on injured reserve, dealing a major blow to the 49ers as they navigate key injuries.

San Francisco 49ers wide receiver Brandon Aiyuk posted a video to his YouTube channel on Monday, providing an update on his ...

It's not surprising in the wake of Brandon Aiyuk's season-ending injury that there has been plenty of talk about how they ...

San Francisco 49ers wide receiver Brandon Aiyuk gave fans an update on his recovery via his YouTube channel one week after ...

Christian McCaffrey is set to make his season debut for the San Francisco against the Tampa Bay Buccaneers on Sunday. How ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee ...

A rough season for Brandon Aiyuk just got worse. The star San Francisco 49ers receiver, who held out until getting a $120 million extension before the start of the season, was carted off with a ...

The San Francisco 49ers lost standout receivers Brandon Aiyuk and Deebo Samuel during Sunday's 28-18 loss to the visiting ...

SANTA CLARA — The 49ers’ already depleted offense has taken two more hits. San Francisco announced that wide receivers Brandon Aiyuk (knee) and Deebo Samuel (illness) have been ruled out for ...