Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could ...

Study shows how telomerase can run amok, deleteriously capping damaged DNA, were it not for a first responder to DNA damage. The natural ends of chromosomes appear alarmingly like broken DNA, much as ...

STOCKHOLM (Reuters) - Three Americans won the Nobel prize for medicine on Monday for revealing the existence and nature of telomerase, an enzyme that helps prevent the fraying of chromosomes that ...

Even the most commonly mutated tumor suppressor genes, such as p53 and Rb, malfunction in only about half of all tumor types. However, excess telomerase appears in all major cancers. So why don't more ...

A day in the life of DNA can be rough. It gets yanked across a dividing cell, zapped by radiation, and assaulted by chemicals. Luckily, cells have developed a complex set of repair mechanisms to ...

Two years ago, Nextbigfuture highlighted Maia Biotechnology, which might have the most promising treatment for all cancers. They poison cells that express the telomerase enzyme which indicates ...

Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to ageing been confirmed; defective telomeres ...

Researchers have discovered the mechanism linking the overconsumption of red meat with colorectal cancer, as well as identifying a means of interfering with the mechanism as a new treatment strategy ...

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must have a ...