Fred Hutch Cancer Center scientists have developed an experimental strategy to give genetically engineered CAR T cells help they'd normally find within lymph nodes — but on the go, within the tumor.

After nearly a decade of treatment, a Texas woman reached remission through an FDA-approved cellular therapy for chronic lymphocytic leukemia.

Scientists have uncovered new genetic rules that determine whether the immune system’s “killer” T cells remain powerful long-term defenders or become worn out and ineffective. By building a detailed ...

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block ...

UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block ...

A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 ...

A cancer drug class best known for attacking tumors may also help your immune system remember them better. Researchers at Georgetown University’s Lombardi Comprehensive Cancer Center report that ...

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be ...

In a breakthrough cancer therapy development, scientists at MIT and Harvard Medical School created a new way of designing immune cells that could make “off-the-shelf” cancer medications more potent ...

A newly discovered cancer trick that weakens immunotherapy may be stopped by everyday statins.

Lymph nodes, hundreds of small structures located throughout the body, play a pivotal role in immunity, including anti-tumor immune responses. White blood cells, also known as lymphocytes, reside in ...

Using the fast metabolic glycan labeling (fMGL) technique, AMS-ManNAz-P was incorporated into the terminal sialic acids of various cell-surface glycans on γδ T cells. The modified γδ T cells were then ...