It has long been thought that two enzymes, the kinases CDC7 and CDK2, are both needed to trigger DNA replication in mammalian cells. This view is challenged by evidence that offers a revised view of ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

Researchers have identified a molecular brake that limits DNA replication in healthy cells, revealing how cells prevent a long-suspected replication catastrophe and pointing to a potential ...

Scientists have discovered that DNA behaves in a surprising way when squeezed through tiny nanopores, overturning a long-held ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...